Cheap Flights from Panama City to Guayaquil

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Find the cheapest month or even day of the year to fly to Guayaquil

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Flight deals from Panama City to Guayaquil

Looking for a cheap last-minute deal or the best return flight from Panama City to Guayaquil? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Panama City to Guayaquil

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Guayaquil flights are currently cheapest in May.

Direct flights from Panama City to Guayaquil

Panama City to Guayaquil: Alternative routes

Compare routes from Panama City to Guayaquil below. You may find an airport to fly into that's cheaper, faster, or easier than Guayaquil.

Panama City to Guayaquil: Flight information

The things to know before you go.
Cheapest flight foundج.م.‏ 8,112
Cheapest month to flyMay
Average flight time2 hrs, 17 mins
Most popular airlineCopa
Average flights per week89

Finding cheap flights from Panama City to Guayaquil: Frequently asked questions

The best price we found for a return flight from Panama City to Guayaquil is ج.م.‏ 15,942. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
2 hours and 17 minutes is the average flight time from Panama City to Guayaquil.
Copa, United and KLM fly direct from Panama City to Guayaquil.
As of March 2025, there are 89 flights per week flying from Panama City to Guayaquil.
The cheapest month to fly from Panama City to Guayaquil is usually March 2025.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Guayaquil Airport on Monday, 2 June 2025.
Yes – the average flight time is 2 hours and 17 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Guayaquil but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Guayaquil is around 40 days in advance, so don’t leave your flight to the last minute.
The cheapest airline that flies to Guayaquil is Copa .

Travelling from Panama City to Jose Joaquin de Olmedo Airport (GYE): what you need to know

  • Panama City is home to a couple of airports where you can set off on your adventure. Check out your options for reserving a flight from Panama City to Jose Joaquin de Olmedo Airport (GYE) leaving from Tocumen International Airport (PTY) or Panama Pacifico Airport (BLB).

  • Expect to be travelling for 2 hours 16 minutes. That's the average duration of a direct flight from Panama City to Jose Joaquin de Olmedo Airport.

  • Jose Joaquin de Olmedo Airport is located in Guayaquil. The city's timezone is UTC-5 — the same as Panama City.

  • The most popular route is from Tocumen International Airport (PTY) to Jose Joaquin de Olmedo Airport (GYE), with 49 direct weekly services. If you'd like to head off as soon as possible, the earliest flight from PTY to GYE is the 09:01 Copa option. If you prefer travelling later, the final departure is at 21:25 with Copa.

  • Arrive at the airport on time so you don't miss your flight from Panama City to GYE. Be there at least two hours ahead for international flights and an hour early for domestic departures to avoid sprinting to your gate.

  • During popular months like June, you'll want to get to the airport earlier than normal. Arrive two hours before domestic departures and four hours ahead for an international flight when you fly during peak periods in general.

Airports in Panama City

Tocumen International Airport (PTY)

  • Take the express route from Tocumen International Airport (PTY). Nonstop flights from Panama City to Jose Joaquin de Olmedo Airport (GYE) operate from here.

  • When taking off from PTY, you can take a direct flight from Panama City to Jose Joaquin de Olmedo Airport with Copa.

  • We make it easy to find a flight from Panama City to GYE with a stopover. To see the options leaving from Tocumen International Airport (PTY), uncheck 'Direct flights only.' Then, simply pick a flight offering a stop long enough to see the sights of the city of your choice. Popular stopovers between PTY and GYE include:

    • El Dorado International Airport (BOG)

    • Jorge Chavez International Airport (LIM)

    • Mariscal Sucre International Airport (UIO)

  • The distance from central Panama City to PTY is about 21 kilometres. Use travel apps like Google Maps for the fastest way to get there, whether you're driving or taking public transport.

  • In search of a convenient hotel close to Tocumen International Airport? If you've booked an early flight from Panama City to Jose Joaquin de Olmedo Airport, these stays will have you moments from check-in:

Panama Pacifico Airport (BLB)

  • Planning to leave from Panama Pacifico Airport (BLB)? You can book a direct flight from Panama City to Jose Joaquin de Olmedo Airport (GYE) from this popular hub.

  • Think about adding a stop at El Dorado International Airport (BOG). It's a popular stopover on a flight from Panama City to Jose Joaquin de Olmedo Airport (GYE) departing Panama Pacifico Airport. Use a long layover to explore nearby, or take advantage of a quick break to grab a coffee at an airport cafe.

  • BLB is roughly 16 kilometres from central Panama City. It'll take you 22 minutes or so to reach the terminal when driving from the city centre.

  • Start your holiday early with an extra night away from home. Before catching your flight from Panama City to GYE, unwind in one of these hotels close to Panama Pacifico Airport:

About Jose Joaquin de Olmedo Airport (GYE)

Getting from Jose Joaquin de Olmedo Airport (GYE) to central Guayaquil

  • From Jose Joaquin de Olmedo Airport, Guayaquil is approximately 6 kilometres away. It takes around 10 minutes to reach the centre driving.

  • When travelling by public transport, expect a journey of roughly 20 minutes.

How to find the cheapest flights from Panama City to Jose Joaquin de Olmedo Airport (GYE)

  • For a one-way ticket from Panama City to Jose Joaquin de Olmedo Airport, ج.م.‏ 8,074 is the cheapest price. You can also book a return trip starting from ج.م.‏ 15,868. These are currently the lowest fares but are subject to change based on availability.

  • To secure cheap tickets from Panama City to GYE, book your trip 9 months before the departure date.

  • You'll score the biggest savings on your tickets from Panama City to Jose Joaquin de Olmedo Airport by travelling in June. Take it one step further and use the 'Whole month' search tool to find the cheapest day to fly.

  • Create a Price Alert for cheap flight tickets from Panama City to GYE. You don't need to search every day to see whether fares have dropped. We'll let you know the moment there's a change in price.

  • Tailor your trip with filters. Select your ideal departure and arrival times, airlines and total journey duration. You can also sort results by 'Best,' 'Cheapest' or 'Fastest' flights from Panama City to Jose Joaquin de Olmedo Airport.

The best time to fly from Panama City to Jose Joaquin de Olmedo Airport (GYE)

  • It's time to figure out your travel dates for your flight from Panama City to Jose Joaquin de Olmedo Airport. August is the busiest month for a trip to Guayaquil. If you want a more relaxed atmosphere, go in April.

  • Book your flight from Panama City to GYE for November if you're eager to head to the city during its warmest month. Expect temperatures in Guayaquil to range from 19ºC to 33ºC.

  • If you want to travel in cooler conditions, search for a cheap flight from Panama City to Jose Joaquin de Olmedo Airport in August when temperatures average between 19ºC and 31ºC.

More about Guayaquil

  • Start your Guayaquil trip right by choosing the perfect place to stay. As soon as you've booked your flight from Panama City to Jose Joaquin de Olmedo Airport, browse our selection of hotels including:

  • There are so many things to discover in this city it can be hard to know where to begin. Malecon 2000, Las Penas and Parque Historico Guayaquil are top attractions which should be on every Guayaquil itinerary.

Complete your Guayaquil trip with a car rental

  • Once you've locked in your hotel and cheap flight from Panama City to Jose Joaquin de Olmedo Airport, the next task is choosing one of our car rentals in Guayaquil. Browse the deals and easily compare options on pick-up convenience, price, and more.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.